Irritable bowel syndrome, also known as spastic colon, is a common digestive disorder that involves both the small intestine and the large bowel. (For more information on this disorder, choose “Chronic Erosive Gastritis” as your search term in the Rare Disease Database.) In severe cases of chronic erosive gastritis there may be bleeding from the stomach that can result in anemia. Symptoms of this disorder may include burning or a heavy feeling in the stomach, mild nausea, vomiting, loss of appetite and general weakness. (For more information on this disorder, choose “Primary Sclerosing Cholangitis,” as your search term in the Rare Disease Database.)Ĭhronic erosive gastritis is an inflammatory digestive disorder characterized by multiple lesions in the mucus lining of the stomach. Bacterial infections may be associated with bile duct blockages of primary sclerosing cholangitis.
#BLOATED STOMACH AND FEELING SICK AND TIRED HEADACHE SKIN#
Later symptoms may include a yellow discoloration to the skin (jaundice), fever, chills, and/or itching of the skin. Symptoms of this disorder include abdominal pain, loss of appetite, nausea, vomiting, and/or weight loss. Primary sclerosing cholangitis is a rare collagen disorder involving inflammation and blockage of the bile duct, liver ducts, and gallbladder.
(For more information on this disorder, choose “Ulcerative Colitis” as your search term in the Rare Disease Database.) Weight loss and a decrease in appetite are also associated with ulcerative colitis. Other symptoms may include abdominal pain, cramping, and urgency (tenesmus). There may be abdominal discomfort, along with a change in the frequency and consistency of stools. The initial symptoms of this disorder may include a general feeling of weakness (malaise) and fatigue. Ulcerative colitis is an acute inflammatory bowel disease characterized by diarrhea and blood in the stools because of multiple, irregular ulcerations of the bowel. (For information on this disorder, choose “Crohn’s Disease” as your search term in the Rare Disease Database.) The symptoms of this disorder can be difficult to manage and diagnosis is often delayed. Diarrhea and bleeding from the rectum are common in people who have Crohn’s disease. Symptoms may include vomiting, fever, night sweats, loss of appetite, general weakness, and waves of abdominal pain and discomfort. Comparisons may be useful for a differential diagnosis:Ĭrohn’s disease is an inflammatory bowel disease characterized by severe, chronic inflammation of the intestinal wall or any portion of the gastrointestinal tract. Symptoms of the following disorders can be similar to those of Whipple disease. (For more information on these disorders, choose “Neuropathy, Peripheral” as your search term in the Rare Disease Database.) Damage to the nerves, especially those of the arms and legs (peripheral neuropathy) may also occur. If Whipple disease remains untreated and malabsorption from the small intestine becomes worse, the affected person may have low levels of circulating calcium and magnesium in the blood (hypokalemia and hypomagnesemia) resulting in muscle cramps, convulsions, and twitching (tetany). (For more information on this disorder, choose “Tinnitus” as your search term in the Rare Disease Database.) In rare cases of this disorder, the heart may be affected resulting in congestive heart failure and/or inflammation of the membranes that surround the heart (pericarditis). Symptoms of neurological involvement may include hearing loss, persistent ringing in the ears (tinnitus), and impairment of vision. The central nervous system is affected in the later stages of untreated Whipple disease. (For more information on this disorder, choose “Myoclonus” as your search term in the Rare Disease Database.) Eye movements may be impaired and uncontrolled muscular movements (myoclonus) may occur when Whipple disease has affected the brain or central nervous system. Occasionally, the loss of intellectual skills progresses to dementia. Some people with this disorder may experience a decrease in intellectual abilities, and an impairment of memory, judgment, and/or abstract thought. Other symptoms of Whipple disease may include: abnormally enlarged lymph nodes that are firm but usually not tender, an abnormally enlarged spleen (splenomegaly), increased color (pigmentation) of the skin, a decrease in blood pressure (hypotension), and abnormally high fevers that come and go. Anemia may result due to insufficient levels of iron, and pain may occur in several widely scattered joints (polyarthritis). Weight loss may occur because of a profound lack of appetite (anorexia). Typically there is fat present in the stool (steatorrhea). The major symptoms of Whipple disease include abdominal pain after eating, joint pain, bouts of diarrhea, cough, chest pain, general weakness, and night sweats.
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